In vitro effect of eltrombopag alone and in combination with azacitidine on megakaryopoiesis in patients with myelodysplastic syndrome

Thrombocytopenia is a severe complication for patients with myelodysplastic syndrome (MDS).Eltrombopag increases platelet count in MDS rubbermaid 8 gallon trash can patients but its combination with azacitidine elicited controversial results.We aimed to quantify the colony forming units of megakaryocytes (CFU-Mk) obtained from CD34+ bone marrow cel

read more


Social acceptability of conservation interventions for flatback turtles: comparing expert and public perceptions

Sea turtles are facing significant threats, including anthropogenic warming, predation from feral animals, and sea level rise.While a range of intervention options are available, resource constraints and increasing time pressures means managers face the difficult task of prioritising options.To achieve successful conservation outcomes, managers are

read more

Canadian Society of Nephrology Commentary on the Kidney Disease Improving Global Outcomes 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder

Purpose of review: (1) To provide commentary on the 2017 update to the Kidney Disease Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD); (2) to apply the evidence-based guideline update for implementation wi

read more